Cerebral arteries have different responses in uremic hypertensive rat and SHR.

2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Cerebral arteries have different responses to pressure and flow in uremic hypertensive rats and spontaneously hypertensive rats.

According to a study from England, "Impaired cerebral blood flow autoregulation is seen in uremic hypertension, whereas in nonuremic hypertension autoregulation is shifted toward higher perfusion pressure.

"The cerebral artery constricts in response to a rise in either lumen pressure or flow; we examined these responses in isolated middle cerebral artery segments from uremic Wistar-Kyoto rats (WKYU), normotensive control rats (WKYC), and spontaneously hypertensive rats (SHR).

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